Name: MOTS-c Peptide for Laboratory Research
SKU: 1292
Price: 40.00 USD
Availability: InStock

MOTS-c Peptide for Laboratory Research

$40.00

MOTS-c is a 16-amino-acid mitochondrial-derived peptide encoded within the mitochondrial 12S rRNA gene, and it is used in preclinical laboratory work as a signaling molecule in energy-metabolism, AMPK-pathway, and cellular-stress investigations. It is studied only in cell culture and animal models, and it is not a drug, supplement, or cosmetic.

Real Peptides supplies MOTS-c in a 10mg research vial. Each batch is tested by an independent laboratory, and the certificate for the current lot is published in the lab results section of this site so its identity and purity figures can be reviewed before purchase. Orders ship from U.S. facilities in Florida and California within 24 hours. Purchasers confirm they are 21 or older and are acquiring the material strictly for laboratory research use.

99% Pure | Multi Dose | Finished in the USAMOTS-c peptide is a 16–amino-acid mitochondrial-derived signaling peptide used in preclinical models to probe energy-metabolism, insulin sensitivity, and cellular stress responses. In cell culture and rodent assays, MOTS-c enhances glucose uptake, modulates AMPK pathways, and supports resilience under metabolic stress. Each 10 mg vial is HPLC-verified to ≥ 99% purity, endotoxin-screened (< 0.1 EU/mg), and formulated for laboratory research.
MOTS-c (Mitochondrial Open-Reading-Frame of the 12S rRNA-Type c) is a 16–amino-acid peptide encoded within the mitochondrial genome. It acts as a mitochondrial hormone, signaling through AMPK and other metabolic pathways to regulate glucose and lipid homeostasis. In research settings, MOTS-c is applied to cell-culture, organotypic, and in vivo models to explore its role in metabolic health, insulin sensitivity, and cellular stress responses—all without engaging systemic hormone axes

Why Choose MOTS-c Peptide?

Researchers choose MOTS-c when they need a precise tool for studying mitochondrial-to-nuclear signaling, energy metabolism, and aging-related pathways. Its ability to trigger AMPK activation and downstream gene programs (PGC-1α, Nrf2) makes it ideal for experiments on metabolic syndrome, type-2 diabetes models, and longevity assays. Manufactured in facilities and verified ≥ 99% pure by HPLC—with endotoxin < 0.1 EU/mg—MOTS-c peptide delivers reproducible, high-fidelity data for cutting-edge metabolic research.

What Sets MOTS-c Peptide Apart?
Unlike generic metabolic modulators, MOTS-c is unique as a mitochondrial-derived peptide that directly communicates cellular energy status to nuclear gene programs. Its dual action—enhancing glucose uptake and promoting antioxidant defenses—offers a multi-pathway approach to studying metabolic resilience and aging. With demonstrated stability both lyophilized and in solution, MOTS-c peptide stands out as a next-generation research reagent for dissecting the interplay between mitochondrial health and systemic metabolism.